fluorescence diagnosis

Fluorescence is the basis of many modern methods in the life sciences.

 

Fluorescence is the key technology for many modern methods in the life sciences enabling life functions to be made visible.

 

Non-invasive fluorescence imaging has the potential to provide in vivo diagnostic information for many clinical specialties

 

Fluorescence diagnostics are procedures designed to detect neoplastic tissues based upon spectroscopic recognition of tissue-specific accumulations of natural or artificial fluorescing molecules (fluorophores).

 

Uterine cervical cancer is one of the most common tumors in women. An estimated 500,000 cases of invasive cancer are diagnosed worldwide each year.

 

The high incidence reflects the deficiency of early detection programs used.

 

From 1990 to nowadays a plethora of new diagnostic methods have been tried, including fluorescence spectroscopy, improvements in the cytological techniques, as well as molecular biological tests. Cervical Intraepithelial Neoplasias (CIN) induced by the Human Papilloma Virus (HPV) frequently are not diagnosed by means of the usual techniques. In many medical consulting offices the lack of optimal equipment and of a simple test to diagnose this disease force gynecologists to use laboratory tests that need long waiting time. The aim of this web page is the introduction of new colposcopic system knows as: “actinic light colposcopy” that solves the above problems. The new instrument is specifically for diagnose the cervical intraepithelial neoplasia.

 

Its results are obtained at the same moment that the procedure is performed. Comparative results in this study with 106 women shows rates of false-positives 3% and False-negatives 13%, against the rates of “classical colposcopy” with ranges from 4 to 33% false-positive and 40 to 62% false-negatives.

 

Also it is expected (in nearest future) that the “actinic light colposcope” will be enhanced for a photodynamic therapy (PDT), so diagnosis and treatment will be accomplished at the same moment that the detections is done